Striant

Generic Name: testosterone (Buccal route)

tes-TOS-ter-one

Commonly used brand name(s)

In the U.S.

• Striant

Available Dosage Forms:

• Patch, Extended Release

Therapeutic Class: Endocrine-Metabolic Agent

Pharmacologic Class: Androgen

Uses For Striant

Testosterone are male hormones. Some are naturally produced in the body and are responsible for the growth and development of male sex organs

This medicine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, testosterone is used in certain patients with the following medical conditions:

• Female-to-male transsexualism in patients with gender identity disorder, (person who is born as a woman but adapts to a man's lifestyle, sees herself as a man, and feels like a man instead of a woman)

Before Using Striant

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this medicine have been done only on adult patients, and there is no specific information comparing use of testosterone in children with use in other age groups

Geriatric

This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults. However older men may be at increased risk for development of prostatic hyperplasia and prostatic cancer.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Anisindione


• Bupropion


• Dicumarol


• Paclitaxel


• Paclitaxel Protein-Bound


• Phenprocoumon


• Warfarin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Licorice

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Breast cancer (in males) or


• Prostate cancer—Androgens can cause growth of these tumors.

• Diabetes mellitus (sugar diabetes)—Testosterone may decrease blood sugar levels. Careful monitoring of blood glucose should be done.

• Heart disease or


• Kidney disease or


• Liver disease—These conditions can be worsened by the fluid retention (keeping too much water in the body) that can be caused by androgens. Also, liver disease can prevent the body from removing the medicine from the bloodstream as fast as it normally would. This could increase the chance of side effects occurring.

• Sleep apnea—This condition may become worse, especially in patients with risk factors such as obesity or chronic lung disease.

Proper Use of Striant

Importance of reading the patient directions carefully before using the buccal system

Proper administration technique

Proper dosing. Use this medicine only as directed.

Proper storage

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For buccal dosage form:
  
  • For testosterone hormone replacement in men
    
    • Adults—30 milligrams (mg) applied to your upper gum above the left or right incisor twice a day
    
    
  
  

Missed Dose

Call your doctor or pharmacist for instructions.

If the buccal system fails to properly adhere to the gum or should fall off during the 12-hour dosing interval, the old one should be removed and a new buccal system applied. If the old one falls out within 4 hours before the next dose, a new system should be applied and it may remain in place until the time of the next regularly scheduled dosing. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Striant

If you will be taking this medicine for a long time, it is very important that your doctor check you at regular visits to check your progress during therapy.

For patients with diabetes mellitus (sugar diabetes), this medicine may lower blood sugar levels. If you notice a change in the results of your blood or urine sugar tests or if you have any questions, check with your doctor.

Tell your doctor if you have too frequent or persistent erections of the penis.

Tell your doctor if you have any nausea, vomiting, changes in skin color or swelling of the ankles.

Tell your doctor if you experience any breathing problems, including those while you sleep.

Regularly check your gums where the buccal system is applied to check for any abnormalities and report findings to your doctor.

Striant Side Effects

Symptoms of Overdose

Get emergency help immediately if any of the following symptoms of overdose occur:

• Blurred vision


• headache


• sudden and severe inability to speak


• seizures


• slurred speech


• temporary blindness


• weakness in arm and/or leg on one side of the body, sudden and severe

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

• Gum or mouth irritation

Less common

• Abnormal liver function test


• abnormal renal function


• bad unusual or unpleasant (after) taste


• bleeding gums


• blemishes on the skin, pimples


• blurred vision


• breast enlargement


• breast pain


• buccal inflammation


• change in taste


• cough


• crying


• depersonalization


• diarrhea


• difficulty breathing


• discouragement


• dry mouth


• dizziness


• dysphoria


• euphoria


• fear


• feeling sad or empty


• fever or chills


• gum blister


• gum pain


• headache


• hoarseness


• indigestion


• irritability;


• itching skin


• loss of appetite


• loss of interest or pleasure


• lower back or side pain


• mental depression


• mouth ulcers


• nausea


• nervousness


• noisy breathing


• paranoia


• painful or difficult urination


• passing of gas


• pounding in the ears


• quick to react or overreact emotionally


• rapidly changing moods


• redness and swelling of gums


• shortness of breath


• slow or fast heartbeat


• stomach cramps


• stomach pain, fullness or discomfort


• stinging of lips


• swelling of gums


• swelling or inflammation of the mouth


• swelling of the nose


• taste bitter


• tightness in chest


• tiredness


• toothache


• trouble concentrating


• trouble sleeping


• unusual tiredness or weakness


• vomiting


• wheezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Striant side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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More Striant resources

• Striant Side Effects (in more detail)
• Striant Use in Pregnancy & Breastfeeding
• Drug Images
• Striant Drug Interactions
• Striant Support Group
• 0 Reviews for Striant - Add your own review/rating

• Striant MedFacts Consumer Leaflet (Wolters Kluwer)


• Striant Prescribing Information (FDA)


• Striant Consumer Overview


• Testosterone Prescribing Information (FDA)


• Testosterone Professional Patient Advice (Wolters Kluwer)


• Testosterone Monograph (AHFS DI)


• AndroGel Prescribing Information (FDA)


• AndroGel Gel MedFacts Consumer Leaflet (Wolters Kluwer)


• Androderm Prescribing Information (FDA)


• Androderm Patch MedFacts Consumer Leaflet (Wolters Kluwer)


• Androgel Consumer Overview


• Axiron Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• Axiron Consumer Overview


• Axiron Prescribing Information (FDA)


• Delatestryl MedFacts Consumer Leaflet (Wolters Kluwer)


• Delatestryl Prescribing Information (FDA)


• Depo-Testosterone MedFacts Consumer Leaflet (Wolters Kluwer)


• Depo-Testosterone Prescribing Information (FDA)


• Fortesta Gel MedFacts Consumer Leaflet (Wolters Kluwer)


• Fortesta Consumer Overview


• Testim Gel MedFacts Consumer Leaflet (Wolters Kluwer)


• Testim Prescribing Information (FDA)


• Testosterone Cypionate Prescribing Information (FDA)


• Testosterone Enanthate Prescribing Information (FDA)

Compare Striant with other medications

• Hypogonadism, Male

Sedapap

Generic Name: acetaminophen and butalbital (a SEET a MIN oh fen and bue TAL bi tal)

Brand Names: Bupap, Cephadyn, Marten-Tab, Phrenilin, Phrenilin Forte, Promacet, Sedapap

What is Sedapap (acetaminophen and butalbital)?

Acetaminophen is a pain reliever and fever reducer.

Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache.

The combination of acetaminophen and butalbital is used to treat tension headaches. This medicine is not for treating headaches that come and go.

Acetaminophen and butalbital may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Sedapap (acetaminophen and butalbital)?

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Tell your doctor if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen.

Before you take acetaminophen and butalbital, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease, a stomach or intestinal disorder, or a history of drug or alcohol addiction.

Butalbital may be habit-forming and should be used only by the person it was prescribed for. Never share this medication with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Tell your doctor if the medicine seems to stop working as well in relieving your pain.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

What should I discuss with my healthcare provider before taking Sedapap (acetaminophen and butalbital)?

Do not use this medication if you are allergic to acetaminophen (Tylenol) or butalbital, or if you have porphyria. Tell your doctor if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen. Butalbital may be habit-forming and should be used only by the person it was prescribed for. Never share this medication with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

To make sure you can safely take acetaminophen and butalbital, tell your doctor if you have any of these other conditions:

• liver disease;


• kidney disease;


• 
  

  a stomach or intestinal disorder; or

  
  


• 
  

  a history of drug or alcohol addiction.

  
  

Tell your doctor if you drink more than three alcoholic beverages per day or if you have ever had alcoholic liver disease (cirrhosis). You may not be able to take medication that contains acetaminophen.

FDA pregnancy category C. It is not known whether acetaminophen and butalbital will harm an unborn baby, but it can cause seizures in a newborn if the mother takes the medication late in pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Acetaminophen and butalbital can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more sensitive to the effects of this medicine.

How should I take Sedapap (acetaminophen and butalbital)?

Take exactly as prescribed by your doctor. Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain. Take this medicine with a full glass of water. Do not stop using acetaminophen and butalbital suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using this medication.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using acetaminophen and butalbital.

If you need surgery, tell the surgeon ahead of time that you are using acetaminophen and butalbital. You may need to stop using the medicine for a short time. Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Butalbital is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Since acetaminophen and butalbital is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen and butalbital can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include extreme drowsiness, confusion, fainting, shallow breathing, or no breathing.

What should I avoid while taking Sedapap (acetaminophen and butalbital)?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Sedapap (acetaminophen and butalbital) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  fast or pounding heart rate, feeling short of breath;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  confusion, depression;

  
  


• 
  

  feeling restless, excited, or agitated;

  
  


• 
  

  seizure (convulsions); or

  
  


• 
  

  nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects include:

• 
  

  headache, dizziness, drowsiness, shaky feeling;

  
  


• 
  

  drunk feeling;

  
  


• 
  

  vomiting, constipation;

  
  


• 
  

  heartburn, trouble swallowing;

  
  


• 
  

  numbness or tingly feeling;

  
  


• 
  

  dry mouth;

  
  


• 
  

  sweating or urinating more than usual;

  
  


• 
  

  leg pain, tired muscles;

  
  


• 
  

  stuffy nose, ear pain, ringing in your ears; or

  
  


• 
  

  mild itching.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sedapap (acetaminophen and butalbital)?

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by butalbital. Tell your doctor if you regularly use any of these medicines.

Tell your doctor about all other medicines you use, especially:

• 
  

  an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate).

  
  

This list is not complete and other drugs may interact with acetaminophen and butalbital. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Sedapap resources

• Sedapap Side Effects (in more detail)
• Sedapap Use in Pregnancy & Breastfeeding
• Drug Images
• Sedapap Drug Interactions
• Sedapap Support Group
• 0 Reviews for Sedapap - Add your own review/rating

• Axocet MedFacts Consumer Leaflet (Wolters Kluwer)


• Cephadyn Advanced Consumer (Micromedex) - Includes Dosage Information


• Phrenilin Prescribing Information (FDA)


• Tencon Prescribing Information (FDA)

Compare Sedapap with other medications

• Headache

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen and butalbital.

See also: Sedapap side effects (in more detail)